Table 4.

Eosinophil gene expression in vitro after cytokine stimulation

Gene	IL-5	IL-4	IFN-γ	GM-CSF	Eotaxin
CD44†	○	○	×	○	×
GM-CSF R α chain†	○	○	×	×	×
GM-CSF R β chain†	○	○	○	○	×
IL-3 Rα chain†	○	○	○	○	×
PAF R†	○	×	ρ	ρ	×
bcl-2†	○	ρ	ρ	×	×
bcl-xL†	○	○	○	○	×
bax‡	×	×	×	×
IL-5 Rα chain‡	×	ρ	×	×	×
IFN-γ R‡	×	×	×	×
CCR3‡	×	×	×	×
VLA4‡	×	×	×	×

×, Not increased; ρ, marginally increased; ○, significantly increased.

^†Higher in AD patients than in healthy volunteers;

^‡similar in both AD patients and healthy volunteers.