Reactivity of sera from mice immunized with human and mouse dsg3 against dsg3 proteins. (a, c) Reactivity of mouse anti-hdsg3 antibodies with human and mouse dsg3. (b, d) Reactivity of mouse anti-mdsg3 antibodies with human and mouse dsg3. (a, c) •, Mouse 1: hdsg3; ⋄, mouse 2: hdsg3; □, mouse 3, hdsg3; ○, mouse 4: hdsg3. (b, d) •, Mouse 1: mdsg3; ⋄, mouse 2: mdsg3; □, mouse 3, mdsg3; ○, mouse 4: mdsg3.