Table 2.
Values of parameters in stimulated and unstimulated cultures of patient and control groups
| IHH (pretreatment)(n=15) | IHH (post-treatment)(n=15) | IHH (controls)(n=15) | ||||
|---|---|---|---|---|---|---|
| Parameters | Stimulated | Unstimulated | Stimulated | Unstimulated | Stimulated | Unstimulated |
| IL-1β (pg/ml) | 67·9 ± 27·5 | 922 ± 320* | 70·8 ± 32·2 | 574·5 ± 311·7† | 77·7 ± 33·3 | 418·6 ± 270·9‡ |
| TNF-α (pg/ml) | 105·8 ± 37·2 | 2149 ± 647§ | 101·8 ± 32·2 | 1356·2 ± 459·2¶ | 95·1 ± 49·1 | 1196·0 ± 720** |
Values represent mean ± standard deviation (s.d.).
IHH, idiopathic hypogonadotropic hypogonadism; IL-1βinterleukin-1β; TNF-α, tumour necrosis factor-α.
P < 0·001 for comparisons of unstimulated and stimulated cultures in all groups.
P < 0·05 for comparisons of unstimulated cultures in all groups.
P = 0·008 for *versus †P < 0·001 for *versus‡ P = 0·191 for †versus‡.
P = 0·001 for §versus ¶ P = 0·001 for § versus** P = 0·052 ¶versus **.