Table 2.
In vivo antibody responses to S. aureus components following intradermal inoculation with TSST-1 secreting S. aureus in congeneic mice with respect to γ/δ TCR expression
| Staphylococcal cell wall antibody* | TSST-1 antibody* | ||||
|---|---|---|---|---|---|
| Size of inoculum (CFU) | Mice | Day 2 | Day 7 | Day 2 | Day 7 |
| 4 × 108 | γ/δ-/- | 30 300 ± 7513 | 59 090 ± 29 102 | 805 ± 473 | 1226 ± 634 |
| n.s. | n.s | n.s. | n.s. | ||
| γ/δ+/− | 33 458 ± 11 137 | 74 812 ± 17 013 | 634 ± 64 | 1331 ± 331 | |
| 4 × 107 | γ/δ-/- | 25 437 ± 4905 | 36 600 ± 12 567 | 446 ± 38 | 1107 ± 270 |
| n.s. | n.s. | n.s. | P = 0·05 | ||
| γ/δ+/− | 33 500 ± 14 285 | 34 650 ± 16 570 | 529 ± 124 | 642 ± 221 | |
*
IgM, arbitrary units ± s.d.