Table 2.
Statistical correlations between cytokines concentrations in the PBMC supernatants used as stimulus (IL-6, IL-8, IL-13, TNF-α and IFN-γ) and the consequent expression of eotaxin, IL-6, IL-8, CD54, CD106, and CD40 by fibroblasts
| Fibroblast expression | ||||||
|---|---|---|---|---|---|---|
| PBMC release | Eotaxin | IL-6 | IL-8 | CD54 | CD40 | CD106 |
| IL-6 | 0·1 | 0·05* | 0·004** | 0·02* | 0·3 | 0·2 |
| IL-8 | 0·07 | 0·06 | 0·02* | 0·004** | 0·5 | 0·2 |
| IL-13 | 0·1 | 0·004** | 0·08 | 0·6 | 0·2 | 0·1 |
| TNF-α | 0·007** | 0·6 | 0·9 | 0·08 | 0·09 | 0·4 |
| IFN-γ | 0·03* | 0·03* | 0·008** | 0·005** | 0·03* | 0·02* |
Values of cytokine concentrations from both Dp stimulated and non-stimulated PBMC supernatants are included in the calculations. A Spearman's rank correlation test was used
a P-value = 0·05 was considered as significant.
P-value = 0·01 as highly significant