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Induction of IL-6 and IL-8 production in fibroblasts by recombinant TNF-α and IFN-γ, respectively, or PBMC supernatants with a comparable amount of these cytokines. One representative experiment of four is shown
| Fibroblast expression | ||
|---|---|---|
| IL-6 | IL-8 | |
| Supernatant (708 pg/ml TNF-α) | 21 146 | 79 098 |
| 750 pg/ml rTNF-α | 6 336 | 16 873 |
| Supernatant (621 pg/ml IFN-γ) | 29 852 | 190 643 |
| 750 pg/ml rIFN-γ | 328 | 363 |
