Table 1.

Percentage and mean fluorescence intensity of CD40L expression on CD8⁻ subpopulation in the three families; for the two-colour analysis a gate was set on activated lymphocytes

	CD4+CD40L+ (%)	Arithmetic mean	Geometric mean
Family 1
Mother	49	96	40·7
Patient 1	40	45	37
Patient 2	49	53	35
Sister	66	407	177
Healthy control	50	212	119
Family 2
Mother	71	409	186
Patient	52	119	53
Healthy control	73	424	200
Family 3
Mother	10	32·6	26
Sister	16	67	39·6
Healthy control	59	127	82