Table 2.
. Median differential cell counts with interquartile range (IQR) in 84 BAL samples from 28 lung allograft recipients grouped as (a) patients with mild (A2) acute rejection (AR) or their matched controls (controls) without AR and (b) patients with obliterative bronchiolitis (OB) or their matched controls (controls) without OB, respectively
| Group | Median sampling time (months) | Lymphocytes (%) | Macrophages (%) | Neutrophils (%) | Eosinophils (%) | |
|---|---|---|---|---|---|---|
| (a) | AR | |||||
| Controls | 4 | A 0 | 3·5 (8) | 87·5 (11) | 3·5 (7·5) | 0 (0) |
| 6 | A 0 | 5 (7·9) | 91 (13·6) | 7 (5·8) | 0 (0) | |
| 12 | A 0 | 8·5 (6·1) | 80 (12) | 5 (6·5) | 0 (0) | |
| AR | 4 | A 0 | 4 (13·6) | 77 (42·9) | 6·5 (4·1) | 0 (0) |
| 7 | A 2 | 15 (28·9)* | 78 (29·4)* | 4·5 (5) | 0 (0) | |
| 12 | A 0 | 15 (17·1) | 82 (12) | 1 (5·1) | 0 (0) |
| (b) | OB | |||||
| Controls | 3 | – | 2·5 (6·0) | 89·0 (25·9) | 3·5 (7·0) | 0 (0) |
| 9 | – | 10·0 (16·3) | 80·0 (26·4) | 5·0 (1·6) | 0 (0) | |
| 18 | – | 7·0 (20·8) | 86·0 (14·5) | 7·0 (3·0) | 0 (0) | |
| OB | 3 | – | 8·0 (17·5) | 80·0 (15·5) | 2·0 (5·5) | 0 (0·3) |
| 9 | – | 51·0 (45·3)* | 47·0 (46·5) | 3·0 (1·3) | 0 (0·3) | |
| 18 | + | 11·5 (30·0) | 64·0 (18·5)* | 22·0 (18·0)* | 0·5 (1·0) |
*
Statistically significant difference compared to patients without acute rejection (Wilcoxon's signed-rank: P < 0·05).