Table 3.
Prevalence of ANCA detected by anti-IgG and anti-IgA secondary antibodies in patients with primary sclerosing cholangitis (with IBD/without IBD) and autoimmune hepatitis
| Primary sclerosing cholangitis | ||||
|---|---|---|---|---|
| total (n = 35) | with IBD (n = 21) | without IBD (n = 14) | Autoimmune hepatitis (n = 40) | |
| IgA ANCA only | 1/35 (3%) | 1/21 (5%) | 0/14 (0%) | 2/40 (5%) |
| IgG ANCA only | 21/35 (60%) | 11/21 (52%) | 10/14 (71%) | 16/40 (40%) |
| IgA and IgG ANCA | 6/35 (17%) | 4/21 (19%) | 2/14 (14%) | 18/40 (45%) |
| Total ANCA positive | 28/35 (80%) | 16/21 (76%) | 12/14 (86%) | 36/40 (90%) |
| Total ANCA negative | 7/35 (20%) | 5/21 (24%) | 2/14 (14%) | 4/40 (10%) |
ANCA, antineutrophil cytoplasmic antibody; IBD, inflammatory bowel disease.