Fig. 3.
Lymphoproliferation in spleen cell cultures from sensitized and tolerized mice. T cell proliferation was measured in spleen cell cultures after in vitro stimulation with rHev b 1 or rHev b 3 for 4 days. Open bars (sens) represent mean SI of five mice sensitized with rHev b 1/Al(OH)3 or rHev b 3/Al(OH)3. Black bars (tol) show mean SI of five mice i.n. treated with rHev b 1 or rHev b prior to sensitization. Error bars indicate s.e.m. *P < 0·05 as determined by the Mann–Whitney U-test. SI = stimulation index.