Table 1.
Theoretical example of analysis of pneumococcal serotype- specific data using the 9- and 7-valent algorithm
Serotype | IgG level to individual serotype | Contribution to IPD caused by serotypes in the 9-valent or 7-valent vaccine (%) † |
---|---|---|
Patient Y (Age group: 65–74 years) | ||
1 | 0·37 | 5·4 |
4 | 0·06 | 10·1 |
5 | 0·37 | 0·0 |
14 | 0·06 | 32·1 |
19F | 0·23 | 6·0 |
23F | 0·21 | 12·5 |
6B | 0·28 | 12·5 |
18C | 1·82 | 5·4 |
9 V | 0·15 | 16·1 |
Individual susceptibility (%) | 58·3 | |
Patient X (Age group: 1–2 years) | ||
4 | 2·44 | 4·5 |
14 | 0·17 | 46·6 |
19F | 0·65 | 14·8 |
23F | 4·38 | 6·8 |
6B | 0·08 | 14·8 |
18C | 5·07 | 9·1 |
9 V | 0·28 | 3·4 |
Individual susceptibility (%) | 61·4 |
9-valent vaccine for Patient Y and 7-valent vaccine for patient X.