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. 2003 Oct;134(1):46–52. doi: 10.1046/j.1365-2249.2003.02267.x

Fig. 1.

Fig. 1

Sequence and alignment of mutant and normal DNASEs. Left register depicts wild-type (a, yellow) and 89I (b, green) sequence traces from BL/6 and MRL-lpr, respectively. The ACA to ATA transition at bp 438 encodes the non-conservative substitution isoleucine for threonine as shown in the (c). (c) Alignment shows alteration superimposed occurs relative to other Dnase1l3 and annotated bovine DNASE 1. Full alignments of human DNASEs can be found in (9).