Table 1.

Intracellular MTSA-10 down-regulates B7·1 expression on J774 cells. Constitutive expression of B7·1, B7·2 or ICAM-1 in MTSA-transfected, mock-transfected or normal J774 cells was determined by flow cytometry. Results are presented as mean values ± s.d. from four independent experiments

	Normal cells	Mock-transfected	MTSA-transfected
% of B7·1+ cells	77 ± 14	71 ± 16	47 ± 11*
Mean fluorescence	195 ± 40	180 ± 28	104 ± 17*

^*P < 0·05: normal and mock-transfected cells.