Table 2.
Monocyte intracellular IL-8 and TNF-α production expressed as percentage of positive cells and geometric mean fluorescence
Percentage of positive cells | Geometric mean fluorescence | ||||||
---|---|---|---|---|---|---|---|
Samples | Number | IL-8 | TNF-α | IL-8 | Range | TNF-α | Range |
Normal | 29 | 39·6 ± 16·0 | 84·5 ± 7·7 | 29·7 | 4·0–59·3 | 609·7 | 80·9–1604·7 |
Relapse | 28 | 29·9 ± 22·8a,b | 67·0 ± 14·0c,d | 32·6 | 4·2–113·0 | 203·5c,e | 24·2–706·2 |
Remission | 27 | 48·2 ± 19·4 | 80·4 ± 11·4 | 34·7 | 4·4–74·2 | 369·5f | 22·9–1003·4 |
P < 0·02, comparing nephrotic relapse with normal controls;
P < 0·002, comparing nephrotic relapse with remission;
P < 0·001, comparing nephrotic relapse with normal controls;
P < 0·001, comparing nephrotic relapse with remission;
P < 0·03, comparing nephrotic remission with normal controls.