Table 1.
Relative expression of CD212 [interleukin (IL)-12Rβ1] and IL-18Rα within the CD4+/CD8+ ‘naïve’ and ‘memory’ subpopulations (CD45RA/CD45RO)
| CD4/CD45RA (95% CI) | CD4/CD45RO (95% CI) | CD8/CD45RA (95% CI) | CD8/CD45RO (95% CI) | |
|---|---|---|---|---|
| CD212 (IL-12Rβ1) | ||||
| Controls (n = 12) | 6·5 ± 1·71 | 34·3 ± 3·80 | 23·6 ± 3·80 | 51·0 ± 2·94 |
| (2·46–10·03) | (25·9–42·7) | (15·3–32·0) | (44·6–57·8) | |
| CVID (n = 31) | 23·6 ± 5·34 | 39·0 ± 2·87 | 40·0 ± 5·14 | 57·1 ± 4·58 |
| (11·9–35·2) | (32·9–45·4) | (28·8–51·4) | (47·6–67·8) | |
| Asthma (n = 20) | 7·1 ± 1·23 | 33·9 ± 3·01 | 22·1 ± 3·29 | 41·8 ± 3·96 |
| (4·51–9·69) | (27·6–40·3) | (15·21–28·9) | (33·5–50·1) | |
| IL-18Rα | ||||
| Controls (n = 12) | 10·8 ± 1·51 | 47·0 ± 2·32 | 15·7 ± 1·81 | 40·9 ± 1·96 |
| (7·43–14·2) | (41·7–52·2) | (11·7–19·7) | (22·9–51·8) | |
| CVID (n = 31) | 20·6 ± 3·80 | 46·6 ± 3·78 | 14·6 ± 1·73 | 27·5 ± 3·10 |
| (12·3–29·0) | (35·3–52·0) | (10·8–18·4) | (17·7–31·3) | |
| Asthma (n = 20) | 11·4 ± 1·20 | 43·8 ± 2·30 | 14·9 ± 1·52 | 36·4 ± 3·69 |
| (8·9–13·9) | (38·9–48·6) | (11·7–18·4) | (28·7–44·1) | |
CI, confidence interval; CVID, common variable immunodeficiency; n, number of patients.
Data are expressed as mean ± standard error of the mean (95% CI).