Table 2.

The presence of malignancies among NBS patients

	NBS
Malignancies	Group A n = 34	Group B n = 7
Malignancy: total †	15/34	5/7
Lymphoid origin	14/15	5/5
B cell (B-NHL; B-LBL/ALL)	8*/14	3/5
T cell (T-NHL; T-LBL/ALL	5/14	1/5
Hodgin's disease	1/14	1/5
Solid tumour (medulloblastoma)	1/15	–
Median age at diagnosis of malignancy: years (range)	8·5 (4·0–24)	8·0 (4·5–12·5)
Death due to cancer or complication of therapy	10/15**	5/5
Median age at death: years (range)	11·0 (4·0–20·5)	8·0 (4·5–12·5)

^†Two further cases suspected clinically (no autopsy performed).

^*Relapse of the same type of lymphoma in two patients,

^**five patients alive (under remission or therapy).