Table 3.

Phenotypic characteristics of lymphocytes in controls and NBS patients

Lymphocyte types	Control (C) n = 40	NBS (A) n = 36 P1	NBS (B) n = 7 P2	P3
Lymphocytes
% (average ± s.d.)	45 ± 9	24 ± 8***	44 ± 10	P < 0·001
Abs.cell count/mm3
(geom. mean)	3355	1365***	3391	P < 0·001
	< 3094÷3638 >†	< 1206÷1545 >	< 2858÷4025 >
CD3+
% (average ± s.d.)	77 ± 6	43 ± 13***	51 ± 19***	P < 0·05
FI	22·1 ± 4·9	18·7 ± 5·7	20·2 ± 5·9
Abs.cell count/mm3	2683 ± 713	650 ± 237***	1670 ± 698***	P < 0·001
CD4+
% (average ± s.d.)	48 ± 7	23 ± 7***	28 ± 19***	P = 0·95
FI (geom. mean)	32	34	31
	< 31·2÷34·3 >	< 31·7÷37·9 >	< 29·6÷32·5 >
Abs. cell count/mm3	1610	329***	835***	P < 0·001
	< 1610÷1539 >	< 283÷383 >	< 5021÷389 >
CD8+
% (average ± s.d.)	27 ± 5	23 ± 6	25 ± 12
FI	42·2 ± 5·3	27·9 ± 7·6**	28·1 ± 7·2**	P = 0·95
Abs. cell count/mm3	911 ± 198	344 ± 140**	921 ± 674	P < 0·001
CD4/CD8 ratio (geom. mean)	1·8	0·8***	1·4*	P < 0·01
	< 1·7÷1·9 >	< 0·7÷0·9 >	< 0·2÷1·5 >
CD56+
% (average ± s.d.)	8 ± 3	31 ± 10***	28 ± 12***	P = 0·68
FI	7·05 ± 2·2	7·1 ± 1·8	7·6 ± 1·9
Abs. cell count/mm3 (geom. mean)	245	407***	992***	P < 0·001
	< 215÷278 >	< 332÷500 >	< 652÷1510 >

^*P < 0·05,

^**P < 0·01,

^***P < 0·001, FI: fluorescence intensity, %: percentage of cells, bold type: statistically significant values,

^†95% CI (confidential interval). Comparisons: P₁: C versus A, P₂: C versus B, and P₃: A versus B.