Table 2.
Cell phenotype staining in leprosy skin
| Classificationb | No. of patients | CD68 (% positive cells ± s.d.) | CD4 (% positive cells ± s.d.) | CD8 (% positive cells ± s.d.) | CD4 : CD8 ratio |
|---|---|---|---|---|---|
| TT | 3 | 38·5 ± 3·3 | 57·7 ± 3·4 | 19·8 ± 2·7 | 2·9 |
| BT | 5 | 36·1 ± 11·3 | 46·7 ± 12·9 | 19·6 ± 14·6 | 2·4 |
| BT-RR | 4 | 47·8 ± 11·1 | 55·2 ± 14·7 | 28·5 ± 8·6 | 1·9 |
| BL | 7 | 50·1 ± 10·4 | 41·5 ± 6·7 | 33·3 ± 6·6 | 1·2 |
| BL-RR | 5 | 53·9 ± 11·9 | 55·2 ± 13·7 | 34·1 ± 6 | 1·6 |
| LL | 4 | 43·8 ± 4·5 | 51·3 ± 5·6 | 30·1 ± 14·3 | 1·7 |
Percentage of positive cells was estimated by microscopic evaluation of several fields corresponding to >500 cells per section.
b
TT, tuberculoid leprosy; BT, borderline tuberculoid leprosy; BT-RR, borderline tuberculoid leprosy in reversal reaction; BL, borderline lepromatous leprosy; BL–RR, borderline lepromatous leprosy in reversal reaction; LL, lepromatous leprosy.