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. 2003 Dec;134(3):470–476. doi: 10.1111/j.1365-2249.2003.02329.x

Fig. 1.

Fig. 1

CD69 expression on NK cells. Flow cytometric analysis of gated CD3-CD56+ NK cells. (a) Titration of IL-2 (▪) or IL-15 (♦) in combination with IL-12 to stimulate CD69 expression in NK cells from a healthy control donor. (b) Flow cytometric profiles are shown of CD69 expression compared to isotype control on gated (left panels) NK cells from a healthy control donor and an HIV-1+ patient receiving HAART only with or without cytokine stimulation. (c) Basal and IL-2 + IL-12-induced NK cell CD69 expression are both reduced significantly in a group of 12 patients on HAART compared to healthy controls. (d) Reduction in MFI for IL-2 + IL-12 and IL-15 + IL-12 stimulation.