Table 2.
Change in mean lymphocyte subset numbers (cells/µl) and sjTREC (copies/µl blood) ± s.d. from baseline over the study in the thymosin and control groups. P-value denotes significance as calculated by the unpaired t-test
| Week 4 | Week 8 | Week 12 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Thymosin | Control | P | Thymosin | Control | P | Thymosin | Control | P | |
| Total CD4 | 12 ± 27 | 26 ± 39 | 0·41 | 51 ± 59 | 43 ± 43 | 0·74 | 30 ± 30 | 51 ± 38 | 0·18 |
| Total CD8 | 119 ± 24 | − 29 ± 339 | 0·25 | 257 ± 305 | 55 ± 165 | 0·15 | 187 ± 150 | 225 ± 244 | 0·67 |
| CD45 RA + CD4+ | 12 ± 17 | 19 ± 16 | 0·39 | 28 ± 29 | 18 ± 14 | 0·51 | − 0·3 ± 17 | 10 ± 15 | 0·22 |
| CD45 RA + CD8+ | − 86 ± 113 | − 115 ± 169 | 0·68 | − 52 ± 151 | 13 ± 188 | 0·48 | − 11 ± 155 | 48 ± 172 | 0·47 |
| CD45 RO + CD4+ | 1 ± 45 | 8 ± 23 | 0·71 | 28 ± 45 | 30 ± 33 | 0·91 | 38 ± 30 | 32 ± 61 | 0·77 |
| CD45 RA + CD8+ | 82 ± 225 | − 64 ± 349 | 0·29 | 160 ± 314 | − 38 ± 138 | 0·21 | 163 ± 107 | 164 ± 270 | 1·00 |
| sjTREC | 3·5 ± 11·1 | 5 ± 7·2 | 0·60 | − 1·3 ± 8·1 | 6·3 ± 7·2 | 0·83 | 27·9 ± 48·3 | − 3·9 ± 7·2 | 0·035 |