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Effects of administration of SR140333 on DNBS-induced colitis in NEPwt and NEP−/− mice assessed by a macroscopic score (A), histological score (B), and measurement of MPO activity in the colon (C) at 3 days after DNBS. ∗∗∗, P < 0.001; ∗∗, P < 0.01; ∗, P < 0.05 compared with control animals that received carrier (Student’s t test).
