Fig 3.

Blood CD4⁺ lymphocyte counts and proportions of CD4⁺IgG⁺annexin⁺7-AAD^– lymphocytes in the blood of 10 long-term HIV-infected haemophilia patients. CD4 counts were negatively associated with the proportion of CD4⁺IgG⁺annexin⁺7-AAD^– blood lymphocytes (Spearman's rank correlation test: r = −0·636; P < 0·05), suggesting that attachment of IgG to CD4⁺ blood lymphocytes induces apoptosis in some lymphocytes with subsequent depletion of these IgG-coated apoptotic CD4⁺ lymphocytes from the circulation.