Table 2.

Sensitivity and specificity of different techniques for AMA detection in PBC patients

	Sensitivity (127 cases)	Specificity (166 + 100 cases)
W-IB	85%†*	97·8%
‘In-House’ ELISA	81·1%	97·8%
Commercial ELISA	78·8%	97·8%
IFL on rat tissue	71·6%*	97·4%
IFL on HEp-2 cells	72·4%†	93·3%

W-IB, Western immunoblotting; IFL, indirect immunofluorescence. The sensitivity has been evaluated in 127 PBC cases, the specificity in 166 type 1 autoimmune hepatitis patients and in 100 patients with non alcoholic fatty liver disease.

^*P = 0·01;

^†P = 0·02.