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Induction of amyloidosis in athymic nude mice. (a) Serum levels of the titre against anti-DNA antibody. (b) Three-colour staining for B220, IgM and IgD in the spleen and bone marrow. The mean and one SD in serum levels of the titre against anti-DNA antibody were produced from 4 mice. After three-colour staining for B220, IgM and IgD, gated analysis was conducted. Numbers in the figure indicate the fluorescence-positive cells in corresponding areas.
