Fig. 1.

Suppression of IgE production by desferrioxamine in HgCl₂-induced autoimmunity. Serum IgE concentration (mean ± s.e.) is shown for groups of BN rats treated with (•) HgCl₂+ saline (▴) HgCl₂+ desferrioxamine, or (◊) saline + desferrioxamine. Rats were injected with (a) one dose of HgCl₂ with (n = 6) or without desferrioxamine (n = 6) (i.p.) or (b) two doses of HgCl₂ with (n = 5) or without desferrioxamine (n = 5) (i.p. and s.c.) or (c) three doses of HgCl₂ with (n = 10) or without desferrioxamine (n = 12) (i.p. and s.c.), or saline with desferrioxamine (n = 6) (i.p. and s.c.).