Fig. 4.

Intravital videomicroscopy evaluation of C-stimulated leucocyte trafficking in FLU-treated rats. Two groups of 8 rats were treated for 15 days with either 5 mg/kg body weight FLU (□) or vehicle (⋄). On the day of the experiment, all rats received an ip injection of LPS (0·25 mg/kg) followed 4 h later by topical application of yeast-activated normal rat serum (50 µl). An additional group of 8 untreated rats received only a topical application of saline 4 h after the ip treatment with LPS (0·25 mg/kg), and served as controls (•). Data of the rolling flux, adhesion and extravasation of leucocytes are expressed as mean ± SD; *P < 0·05, or **P < 0·01, compared with the vehicle-treated animals at each considered time.