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Frequencies of IL-10-secreting cells in 2 × 104 PBMC, 105 CD3+ T cells, 104 monocytes and 105 B cells separated from PBMC stimulated with HBcAg. Open columns are frequencies of IL-10-secreting cells in healthy controls and filled columns are frequencies in patients with chronic HBV infection.*P < 0·05, **P < 0·01. IL, interleukin; PBMC, peripheral blood mononuclear cell; HBV, hepatitis B virus.
