Table 2.
Percentages of cytokine-producing CD3+ T cells. Values indicate the proportion of T lymphocytes located in regions M1 and M2 in CF patients and healthy subjects before and after activation with PMA and ionomycin in whole blood culture
| % of CD3+ cells | ||||||||
|---|---|---|---|---|---|---|---|---|
| Non-activated cells | Activated cells | |||||||
| Controls | CF | Controls | CF | |||||
| Cytokines | M1 | M2 | M1 | M2 | M1 | M2 | M1 | M2 |
| IFN-γ | 98·9 ± 1·7 | 2·6 ± 2·3 | 99·2 ± 0·7 | 2·1 ± 1·7 | 83·3 ± 8·8 | 21·1 ± 11·2 | 79·2 ± 9·7 | 20·3 ± 9·6 |
| IL-2 | 87·9 ± 7·2 | 2·1 ± 0·7 | 85·7 ± 8·1 | 1·8 ± 1·2 | 79·7 ± 15·2 | 11·3 ± 3·8 | 68·0 ± 8·7 | 20·2 ± 1·5 |
| IL-8 | 93·5 ± 2·9 | 2·8 ± 2·4 | 91·6 ± 6·4 | 5·3 ± 5·1 | 78·8 ± 21·3 | 11·7 ± 9·3 | 90·6 ± 5·7 | 6·5 ± 5·9 |