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The effect of ATRA or 9CRA on HT-29 cells is an RAR specific reaction. HT-29 cells were co-stimulated with TNF-α and 1 µm of TTNPB (*P < 0·01) or 1 µm of MA or AM-580 (*P < 0·04) or 4-HPR for 48 h. After cultivation, culture supernatants were subjected to ELISA as described in Materials and methods. Experiments were performed in triplicate.
