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Semi-quantitative RT-PCR of mRNA extracted from the cortex of adriamycin and saline-treated mice 6 weeks after disease induction. There was a significant increase in the ratio of the PCR product for both Col IV (a) and HSP47 (b) compared to β-actin (*P < 0·01 for both, n = 8). (c, d) show PCR gels demonstrating greater intensity in the Col IV (c) and HSP47 (d) PCR products from cortical mRNA derived from adriamycin-treated mice (lane 1) and control mice (lane 2).
