Table 1.

Secretion of fibronectin in HMC (ng/ml)

	12 h	24 h	36 h	48 h
0·5%FCS	3·00 ± 0·05	3·14 ± 0·24	3·23 ± 0·22	3·01 ± 0·27
Nor.aIgA1	3·33 ± 0·21	3·21 ± 0·1	4·83 ± 0·23*†	5·54 ± 0·43*†
Pat.aIgA1	3·22 ± 0·12	3·42 ± 0·06	5·51 ± 0·15**†	6·45 ± 0·18**†

Supernant fibronectin concentration of HMC exposed to 0·5%FCS culture medium alone (0·5%FCS) or with aIgA1 of 100 µg/ml from healthy controls(Nor. aIgA1) or from patients with IgAN (Pat.aIgA1) for different hours. Results shown were means ± 2SE of three different experiments with triplicate wells. The cells were a mixture of six lines and the aIgA1 sample was from pooled sera of 10 healthy controls or 10 patients.

^*P ≤ 0·05 Nor.aIgA1 versus 0·5%FCS

^**P ≤ 0·05, Pat.aIgA1 versus 0·5%FCS or Nor.aIgA1

^†P ≤ 0·05 between different time with in the same group.