Table 2.

Effects of itraconazole on the net influx of ⁴⁵Ca²⁺ in neutrophils activated with FMLP or PAF

System	Net influx of 45Ca2+ (pmol/107 cells/5 min)
Control	55·3 ± 5·8
FMLP (1 µm)	127·6 ± 7·3
Itraconazole (5 µm) + FMLP (1 µm)	116·1 ± 7·3
PAF (200 nm)	210·2 ± 11·8
Itraconazole (5 µm) + PAF (200 nm)	153·2 ± 9·5*

The results are expressed as the mean values ±s.e.m. of 4 different experiments with 5 replicates in each.

^*P < 0·001 for comparison with the corresponding itraconazole-free system.