Table 2.
Mortality rate, mean time to death in different groups of BALB/c mice infected with EV, strain K-1, at a dose of 5 LD50 and treated by different schemes
Group | No. of mce | Mortality rate (%) | MTD (day) |
---|---|---|---|
A1 | 30 | 100 | 9·34 ± 0·32 |
B1 | 30 | 53·3 | 10·52 ± 0·46* |
C1 | 30 | 70 | 10·10 ± 0·40* |
D1 | 30 | 23·3 | 9·34 ± 0·88 |
For schemes of rmTNF-α and rmIFN-γ treatment see Table 1.
Statistically different from the control (P = 0·0086; 0·0421 correspondingly).