Table 1.
Immunlogical data of patients
| Serum Ig (mg/dl)† | Surface Ig-bearing B cells (%) | IgG subclass (mg/dl) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient no. | Sex | Age | IgG | IgA | IgM | IgG | IgA | IgM | IgG1 | IgG2 | IgG3 | IgG4 |
| Selective IgA deficiency | ||||||||||||
| 1 | M | 6 years | 1120 (630–1490) | <5 (45–258) | 110 (72–305) | 1 | 0 | 23 | 619 | 255 | 57·3 | 33·9 |
| 2 | F | 14 years | 1750 (760–1680) | <5 (77–371) | 259 (69–296) | 1 | 1 | 13 | 630 | 625 | 35·1 | 18·4 |
| 3 | F | 7 years | 1430 (660–1340) | <5 (51–279) | 104 (73–310) | 0 | 0 | 5 | 893 | 382 | 47·4 | 59·4 |
| Partial IgA deficiency | ||||||||||||
| 4 | M | 21 months | 889 (460–1220) | 13 (16–128) | 69 (57–260) | 1 | 1 | 3 | 466 | 98.4 | 13·5 | 16·2 |
| 5 | F | 16 months | 465 (460–1220) | 9 (16–128) | 70 (57–260) | 1 | 0 | 5 | 306 | 69.3 | 27·6 | 3·8 |
| 6 | M | 18 months | 474 (460–1220) | 10 (16–128) | 83 (57–260) | 2 | 0 | 11 | 295 | 97.0 | 40·0 | 4·4 |
†
Normal range (2·5–97·5 percentile) of serum Ig are given in brackets where appropriate; they are from Normal Range for Clinical Testing of Japanese Children[15].