Table 2.
C57BL/6 J | TCR-α–/– | TCR-δ–/– | ||||
---|---|---|---|---|---|---|
Group | No. examined | Skin lesion | No. examined | Skin lesion | No. examined | Skin lesion |
1 PBS | 6 | 0/6 | 6 | 0/6 | 6 | 0/6 |
2 Low FU (1 mg/ml) | 11 (1) | 0/10 | 11 (3) | 0/8 | 8 (2) | 0/6 |
3 High FU (10 mg/ml) | 25 (13) | 2/12 | n.d. | n.d. | n.d. | n.d. |
4 UVBL (200 mJ/cm2) | 11 | 1/11 | 9 (1) | 2/8 | 12 | 3/12 |
5 Low FU plus UVBL | 6 | 0/6 | 18 (3) | 9/15 | 13 | 2/13 |
6 High FU plus UVBL | 6 (1) | 4/5 | n.d. | n.d. | n.d. | n.d. |
The incidence of skin lesion was estimated when mice were sacrificed. (): number of dead mice during experiments. n.d.: Data were excluded because of high mortality.