Table 2.
Univariate analysis between changes in total CD4+ T cells and different baseline parameters
| Week 4 (n = 49) | Week 12 (n = 50) | Week 48 (n = 33) | Week 96 (n = 27) | |||||
|---|---|---|---|---|---|---|---|---|
| Variable | r | P | r | P | r | P | r | P |
| Age | −0·032 | 0·826 | −0·239 | 0·095 | 0·072 | 0·692 | −0·850 | 0·674 |
| Total CD4+ counts | 0·180 | 0·216 | 0·094 | 0·517 | −0·048 | 0·791 | −0·109 | 0·589 |
| Total CD8+ counts | −0·041 | 0·778 | −0·260 | 0·068 | −0·348 | 0·047 | −0·342 | 0·081 |
| Naive CD4+ T cells | 0·267 | 0·105 | 0·307 | 0·051 | 0·046 | 0·802 | 0·045 | 0·831 |
| Naive CD8+ T cells | 0·226 | 0·173 | 0·358 | 0·022 | −0·049 | 0·789 | 0·142 | 0·499 |
| Memory CD4+ T cells | 0·070 | 0·676 | −0·013 | 0·934 | −0·086 | 0·640 | −0·125 | 0·552 |
| Memory CD8+ T cells | −0·078 | 0·640 | −0·430 | 0·005 | −0·245 | 0·176 | −0·239 | 0·250 |
| IL-7 levels | −0·215 | 0·194 | −0·060 | 0·710 | −0·146 | 0·425 | −0·107 | 0·609 |
| Viral load | −0·083 | 0·585 | −0·247 | 0·094 | 0·019 | 0·921 | −0·301 | 0·144 |
| Thymic volume | 0·326 | 0·031 | 0·479 | 0·001 | 0·422 | 0·016 | 0·432 | 0·031 |
| TREC+ bearing-cells | 0·152 | 0·361 | 0·084 | 0·602 | −0·174 | 0·342 | 0·175 | 0·402 |
| X4/R5 ratio | −0·084 | 0·712 | −0·105 | 0·632 | 0·081 | 0·774 | 0·489 | 0·107 |
Significant values are underlined (P < 0·1). At weeks 4,12, 24, 48 and 96 a Pearson test was used. TREC, T cell excision circle.