Table 3.

Genes differentially expressed in U937 cells after infection with Mycobacterium avium

			Fold induction at time point (h)
Gene	GenBank ID	Classification	4	12	24
ERBB3	M29366	Tyrosine kinase	3	6·7	4·8
EPHA3	M83941	Tyrosine kinase	–	23	52
PTPN7	D11327	Tyrosine phosphatase	4	3·3	–
LAT	AF036905	Signal transduction	–	3·5	–
CSF1	M37435	Signal molecule	4·6	3	–
ID2	M97796	Transcription factor	–	−4	−3·8
NFKB	X61498	Transcription factor	–	7·7	3·2
ISGF3G	M87503	Transcription factor	–	–	−3·2
JUN	J04111	Transcription factor	–	4	–
SPI1	X52056	Transcription factor	7·8	4·6	–
SPN	J04536	Intracellular signalling	–	−3	−3·4
ARHGDIA	X69550	G protein dissociation inhibitor	–	4·2	–
GNB1	M36430	G protein	–	3·5	10·9
GNB2L1	M24194	G protein	3·1	4·5	2·9
FGF11	U66199	Growth factor	3·4	3·7	–
ITGA5	X06256	Adhesion	–	5·6	–
ITGAL	Y00796	Adhesion/integrin	–	15	3
ICAM1	J03132	Adhesion/signal transduction	–	–	3·7
BCL2L1	Z23115	Apoptosis	–	−19	–
IEX1L	AF039067	Apoptosis	–	5·9	3·1
CASP10	U60519	Apoptosis	–	6·1	–
RPS19	M81757	Ribosomal protein/apoptosis	–	4	–
Neurolukin	K03515	Lymphokine	–	3·5	–
SCYA1(I309) M57502	Cytokine	2·8	3·7	32
TNFA	X01394	Cytokine	–	5·2	3·8
RANTES	M21121	Cytokine	–	4·7	3
GROB(MIP2)	X53799	Cytokine	–	2·7	8·7
IL1B	K02770	Cytokine	–	3	3·8
IL8	Y00787	Chemokine	–	–	4
IL2RG	D11086	Cytokine receptor	–	4·3	–
IL2RA	X01057	Cytokine receptor	–	4·8	3
TNFRSF1B	M32315	Cytokine receptor	–	3	6·8
CDKN1A	U09579	Kinase inhibitor/cell cycle	–	4·1	–
TMP1	X03124	Metalloproteinase inhibitor	–	4·9	2·3
MMP9	J05070	Metalloproteinase	–	5	–
MMP11	X57766	Metalloproteinase	–	9·3	–
CAPN4	X04106	Protease	–	3·7	–
PI	X02920	Protease inhibitor	–	–	3·4
TMSB4X	M17733	Actin polymerization inhibitor	–	−4·5	–
AZU1	X58794	Chemotaxis/antimicrobial	4·2	4	–
AP2M1	D63475	Lysosome acidification	–	−3	−3
CTSD	M11233	Lysosomal protease	–	–	−3·4
MT1H	X64177	Metal binding protein	3·7	2·7	3·3
DTR	M60278	EGF receptor	–	–	6·8