Table 1.
Comparison of DPB between HTLV-I positive patients and negative patients
| HTLV-I positive patients (n = 12) | HTLV-I negative patients (n = 23) | P-value | |
|---|---|---|---|
| White blood cells (/µl) | 8923 ± 2344 | 9211 ± 2564 | n.s. |
| C-reactive protein (mg/ml) | 4·33 ± 2·98 | 3·99 ± 3·01 | n.s. |
| HCV ab. (+) | 1/12 | 2/23 | n.s. |
| HBs ag. (+) | 1/12 | 2/23 | n.s. |
| CMV ab (+) | 0/12 | 0/23 | n.s. |
| Adenovirus ab. (+) | 0/12 | 0/23 | n.s. |
| Mycoplasma ab. (+) | 0/12 | 0/23 | n.s. |
| Pulmonary function tests | |||
| %VC (%) | 73·4 ± 19·8 | 75·3 ± 20·2 | n.s. |
| %FEV1 (%) | 60·8 ± 14·2 | 70·1 ± 13·3 | P < 0·05 |
| Radiographic appearance | |||
| Visual score | 30·4 ± 11·8 | 22·3 ± 13·8 | P < 0·05 |
| Ratio of upper lobe involvement | 10/12 | 8/23 | P < 0·05 |
| BALF analysis | |||
| Total cell count (×105/µl) | 32·2 ± 18·8 | 30·1 ± 17·9 | n.s. |
| Macrophage (%) | 20·3 ± 4·66 | 19·6 ± 4·41 | n.s. |
| Lymphocyte (%) | 16·9 ± 4·44 | 16·1 ± 4·38 | n.s. |
| Neutrophile (%) | 68·1 ± 15·1 | 67·6 ± 14·8 | n.s. |
| CD4+ lymphocytes(%) | 37·8 ± 12·1 | 32·8 ± 14·9 | n.s. |
| CD8+ lymphocytes (%) | 33·1 ± 18·1 | 40·5 ± 14·7 | n.s. |
| CD4+/CD8+ | 1·12 ± 1·11 | 0·83 ± 1·22 | n.s. |
| CD3+ lymphocytes (%) | 89·3 ± 13·3 | 86·9 ± 14·5 | n.s. |
| CD3+/CD25+ (%) | 37·6 ± 14·4 | 20·9 ± 15·6 | P < 0·05 |
| CD4+/CD25+ (%) | 10·2 ± 13·4 | 9·8 ± 13·2 | n.s. |
| CD8+/CD25+ (%) | 27·1 ± 13·2 | 10·8 ± 12·6 | P < 0·05 |
| Infectious pathogens in BALF | |||
| P. aeruginosa | 10/12 | 19/23 | n.s. |
| H. influenzae | 2/12 | 4/23 | n.s. |
| C. albicans | 2/12 | 3/23 | n.s. |
| Mycobacteriums | 0/12 | 0/23 | n.s. |
| Others | 1/12 | 0/23 | n.s. |
CMV: cytomegarovirus, ab. antibody, P. aeruginosa: Pseudomonus aeruginosa. H. influenzae: Haemophillus influenzae, C. albicans: Candida albicans. Others in HTLV-I positive patient: Cryptococcus neoformans.