Table 1.
Antigen specificities of antibodies that have been detected in the serum of patients with antiphospholipid syndrome.
| Antigen/antigen complex | References |
|---|---|
| Phospholipids | |
| Anionic phospholipids (e.g. cardiolipin, phosphatidyl serine) | [1] |
| Zwitterionic phospholipids (e.g. phosphatidyl ethanolamine) | [73] |
| Components and regulators of coagulation and fibrinolysis | |
| Beta 2 glycoprotein I | [23,24] |
| Prothrombin | [44–52] |
| Thrombin | [45,54] |
| Anti-thrombin III/thrombin complex | [55] |
| Tissue factor/factor VIIa complex | [36,37] |
| High and low molecular weight kininogen | [73] |
| Prekallikrein | [55] |
| Sulphatides | [74] |
| Protein Z/protein Z protease inhibitor system | [75] |
| Protein C | [30,57] |
| Protein S | [30] |
| Thrombomodulin | [61,62] |
| Tissue plasminogen activator | [67] |
| Annexin V | [70] |
| Lipoproteins | |
| Oxidized low density lipoprotein | [106,107] |
| High density lipoprotein | [111] |
| Apolipoprotein A-I | [111] |