Table 1.
Quantitative analysis of lung lesions
| Mice injected with† | Pleura thickness‡ | Vasculitis§ | Granulocytes¶ | Eosinophils¶ | Apoptotic cells¶ |
|---|---|---|---|---|---|
| FasL DC | 117 ± 88* | 67 ± 12* | 227 ± 30* | 17·0 ± 13* | 95 ± 17* |
| CTRL-DC | 11 ± 2 | 0 | 125 ± 32 | 0·5 ± 0·8 | 21 ± 5 |
| Saline | 6 ± 2 | 0 | 97 ± 23 | 0·3 ± 0·5 | 19 ± 3 |
Mice received an IV injection of either 1 × 106 C57Bl/6-lpr/lpr FasL-DC (FasLDC), 1 × 106 C57Bl/6-lpr/lpr PIA (CTRL-DC) or saline, n = 8 in each group.
Pleura thickness is expressed in microns, mean ± SD.
Vasculitis is expressed as percentage of inflamed vessels, mean ± SD.
Number of granulocytes, eosinophils and apoptotic cells (antiactive caspase 3 positive cells) per mm2, mean ± SD.
P < 0·05 compared to CTRL-DC.