Table 2. Arthritis-linked phenotypes in naive irradiated animals receiving lymph node (LN) cells of different origins taken at different days postsqualene injection.
| Lymph node cells taken at X days postsqualene injection | ||||
|---|---|---|---|---|
| Arthritis-linked phenotype | Day 5 | Day 8 | Day 11 | Day 14 |
| Incidence percentage (no. of animals) | ||||
| Axillary/brachial LN | 0 (0/3) | 0 (0/6)* | 25 (1/4) | 75 (3/4) |
| Inguinal LN | 0 (0/9) | 67 (10/15) | 75 (6/8) | 88 (7/8) |
| Max score† | ||||
| Axillary/brachial LN | – | – | 2 | 1 (1; 2)* |
| Inguinal LN | – | 1·5 (1; 5) | 2 (1; 5) | 3 (1; 4) |
| Day of onset† | ||||
| Axillary/brachial LN | – | – | 10 | 11 (5; 11) |
| Inguinal LN | – | 11 (8; 25) | 9 (9; 19) | 10 (10; 11) |
†
Values are presented as median (min; max) of arthritic animals only.
*
P < 0·05 compared to animals receiving inguinal LN cells, using the Fischer's exact test for incidence and unpaired Student's T-test for max score, respectively.