Fig. 4.
Activated apoptotic bright (CD3−CD56+brightCD69+annexin-V+) NK and dim (CD3−CD56+dimCD69+annexin-V+) NK cells. Activated apoptotic bright (CD3−CD56+brightCD69+annexin-V+) cells as a percentage of total CD3−CD56+ cells are significantly increased in HCV-infected patients (hatched), NR patients (vertical lines), and SVR patients (horizontal lines) compared to healthy controls (white bar) in the absence of IFN-α stimulation (P < 0·01, p = 0·02, and P < 0·01, respectively). Activated apoptotic dim (CD3−CD56+dimCD69+annexin-V+) cells are increased in SVR patients (horizontal lines) compared to healthy controls (white bar) and NR patients (vertical lines) in the absence of IFN stimulation (P = 0·04 and P = 0·07, respectively). Error bars represent standard error.