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. 2004 Aug;137(2):417–423. doi: 10.1111/j.1365-2249.2004.02544.x

Fig. 2.

Fig. 2

Increased allostimulatory capacity of circulating dendritic cells (DCs) from patients with chronic hepatitis C (CHC) due to antiviral therapy. Circulating DCs were isolated from patients with CHC before the start of therapy and four weeks after the start of antiviral therapy. Levels of incorporation of [3H]-thymidine (in cpm) reflected the levels of blastogenesis in allogenic mixed leucocyte reaction (MLR) containing T cells (2 × 105) from normal volunteer and circulating DCs from patients with CHC (1 × 104). The levels of blastogenesis in cultures containing DCs from patients with HCV before antiviral therapy (DCs from HCV RNA+ patients) are shown as black bars. The levels of blastogenesis in allogenic MLR containing DCs from the same patient, 4 weeks after the start of antiviral therapy (DCs from HCV RNA patients) are shown by clear bars.