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Impaired production of intracellular IFN-α in plasmacytoid DCs from patients with chronic hepatitis C due to stimulation with various doses of herpes simplex virus-1. The numbers of plasmacytoid DCs expressing IFN-α from individual normal control (○) and patient with chronic hepatitis C (•) are plotted in (A). Mean and standard deviation of the data of Figure in (a) is shown in (b). *P < 0·01 compared to normal controls.
