Fig. 2.

RSV depresses interferon-γ production in samples obtained at birth, at 1 year and at 4 years of age. Stem cell- or monocyte-derived dendritic cells were either infected with RSV or mock infected. DCs were cultured with peripheral blood naive T cells and TSST 1 for 3 days. The expression of interferon-γ in TSST 1 reactive Vβ2⁺ cells was measured by flow cytometry. The diagrams shows the results without (control) and with RSV infection in dot-plot as well as box and whiskers. The box delineates the median and the upper and lower quartile, whereas the whiskers delineate the range. The open dots represent values obtained from children without clinical contact with RSV and the closed circles represent values from children after contact with RSV as indicated by a positive serology.