Table 5.
Comparisons of the percentages of CD3+CD25+, CD3+CD69+, and CD3+HLA-DR+ T cells in unstimulated (medium alone) and stimulated (medium + PHA) cell cultures from patients with FMF and controls
| FMF (attack-free) (n = 26*) | FMF (attack) (n = 15*) | Healthy controls (n = 20) | Behçet's disease (n = 15) | |||||
|---|---|---|---|---|---|---|---|---|
| Parameters (%) | Medium | PHA | Medium | PHA | Medium | PHA | Medium | PHA |
| CD3+CD25+ | 4·2 ± 2·2 | 26·4 ± 9·2 | 6·4 ± 2·5 | 23·2 ± 6·9 | 4·6 ± 2·4 | 17·3 ± 8·0 | 4·2 ± 2·3 | 20·0 ± 9·1 |
| CD3+CD69+ | 1·5 ± 1·0 | 52·3 ± 12·7 | 2·3 ± 0·9 | 42·1 ± 11·1 | 1·9 ± 1·2 | 41·5 ± 11·2 | 1·8 ± 0·8 | 37·4 ± 13·7 |
| CD3+HLA-DR+ | 5·6 ± 2·9 | 14·9 ± 6·3 | 6·7 ± 2·3 | 13·8 ± 3·1 | 5·4 ± 1·8 | 6·3 ± 2·8 | 5·0 ± 2·3 | 8·4 ± 3·9 |
CD: cluster of differentiation; FMF: familial Mediterranean fever.
*
With double donors;
**
multiple comparisons were performed using the Kruskall–Wallis test.