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The effect of BCG vaccine dose (CFU/mouse) on protection against virulent tuberculous challenge. BALB/cJCit mice were challenged by exposure to H37Rv aerosol 12 weeks after BCG vaccination. Mean (n = 8) and standard deviation (vertical bars) of CFU counts in the lungs (open squares) and spleens (open circles) at 16 weeks are shown. Limit of detection 0·7 log CFU/organ.
