Table 2.
Concentration of GDPs in PDF and in culture medium
| GDP | MW g/mol | Concentration in conventional PDF (µm)** | Concentration (µm) in cell culture experiments at 1a or 10bµg/ml | Concentration giving < 50% cell viability in cell culture experiments |
|---|---|---|---|---|
| AcA | 44·05 | 120–420 | 227b | 2270 |
| FoA | 30·03 | 6–15 | 33·3a | 3330 |
| FurA | 96·09 | 0·05–2 | 10·4a | 1040 |
| Glx | 58·04 | 3–14 | 17·2a | 1720 |
| M-Glx | 72·08 | 2–23 | 13·9a | 1390 |
| 5-HMF | 126·1 | 6–30 | 78b | 780 |
| 3-DG | 162·1 | 118–154 | 61b | 610 |
| 3,4-DGE | 144·1 | 9–22 | 69b | 690 |
Data adapted from [22] and [26]. Abbreviations: GDPs = glucose degradation products, PDF = peritoneal dialysis fluid, AcA = acetaldehyde, formaldehyde = FoA, FurA = 2-furaldehyde, Glx = glyoxal, methylglyoxal = M-Glx, 5-hydoxymethyl-2-furaldehyde = 5-HMF, 3,4-dideoxyglucosone-3-Ene = 3,4-DGE, 3-deoxyglucosone = 3-DG.