Table 1.
Effect of LEFCT-EC with different chemotherapeutic drugs on the development of CT-26 colon carcinoma
| Average tumour volume (mm3 ± SE)a | ||||||||
|---|---|---|---|---|---|---|---|---|
| Groups | TB mice | LEFCT | 5FU i..t. | 5FU i.v. | LEFCT-EC 5FU i.t. | LEFCT-EC 5FU i.v. | Bleomycin | LEFCT-EC bleomycin |
| Tumour volumeb | 3328 ± 176 | 1782 ± 267 | 780 ± 134 | 461 ± 105 | 118 ± 48 | 119 ± 49 | 1715 ± 208 | 584 ± 146 |
| (68) | (35) | (12) | (6) | (6) | (6) | (19) | (24) | |
| % of survivalc | 0 | 0 | 0 | 0 | 33 | 16 | 0 | 52 |
a
Average tumour volume in all mice in each group (no. of mice).
b
Tumour volume was measured 22–24 days after tumour inoculation. Treatment was given when the tumour volume was 65 mm3(9–12 days after tumour inoculation).
c
Survival 120 days after tumour inoculation.