Fig. 2.
Cl– currents are blocked by volume-sensitive channel blockers. The bathing medium and pipette solution contained CsCl saline. Families of whole-cell Cl– currents were recorded in human monocytes from a holding potential (VH) of 0 mV at command voltage (VC) steps from −100 mV to 60 mv applied every 1 s in 20 mV increments. Control whole-cell Cl– current were recorded before (left panel) and after perfusion of 200 µm NPPB (n = 7) or IAA94 (n = 6, right panel).